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Additional resources for Cornea and External Eye Disease: Corneal Allotransplantation, Allergic Disease and Trachoma
Whereas deep corneal ulcers and corneal perforation historically were absolute indications for penetrating keratoplasty, these conditions can also be managed by using the inlay and multilayer AMT techniques. After healing and re-epithelialization are completed, a penetrating keratoplasty can then be performed for visual rehabilitation. By avoiding the need for a keratoplasty à chaud, the long-term outcome may be improved significantly [6, 10, 62]. To reduce corneal scarring and neovascularization, an additional AMT may be applied as a patch combined with the keratoplasty procedure.
To reduce corneal scarring and neovascularization, an additional AMT may be applied as a patch combined with the keratoplasty procedure. The anti-inflammatory factors liberated from the AM may decrease the risk of postoperative immune reactions . In addition, the AM may prevent neovascularization of the transplant and promote rapid re-epithelialization of the corneal graft. References 1. Bacon AS, Frazer DG, Dart JK, et al. (1993) A review of 72 consecutive cases of Acanthamoeba keratitis, 1984–1992.
N = 4, Pseudomonas, n = 5). The AM was placed after the patient received antibiotic therapy and clinical improvement was observed. In 7 of the 9 patients, the epithelium healed completely. In another patient, a stable corneal surface was noted and in the last patient neovascularization was reduced. Visual acuity improved in 7 of the 9 patients. Three patients received a soft contact lens and two others underwent an additional debridement procedure . Chen and colleagues describe their observa- References tion after AMT in 6 eyes with proven Pseudomonas aeruginosa infection.